This meeting considers the structural biology of the major pathways of DNA repair and their interface with all DNA transactions in cell biology. Topics will stress the involvement of DNA repair complexes in decisions points in cell biology including replication, recombination, and transcription processes. Talks will include the nature of the DNA damage, our understanding of repair detection, signally, and processing mechanisms, and the connections of DNA repair responses and human health.

The structural biology of DNA repair assemblies with their conformations and interactions provides the foundation for a unified understanding of the biochemistry, genetics, and cell biology. Indeed, the structural biology of DNA repair has profound implications for the interpretation of the genetic code, the consequences of DNA mutations in human disease, and the preservation of the species.

Overall, this conference provides a critical opportunity to bring together experts in diverse fields relating to basic mechanisms of DNA repair revealed by the structural biology of the complexes. The outcomes of integrated discussions will be fundamental insights into the challenges and opportunities of DNA repair structures for linking proteins to their biologically relevant states and assemblies.

The focus of the conference will be on the following themes:

- Chromatin Remodeling and DNA repair
- Replication, mismatch repair and genome fidelity
- Nonhomologous end-joining
- Compelling structural and mechanistic questions
- Making Double strand break repair complexes speak
- DNA Damage signaling and processing
- Complex Lesions and Damage response Complexes
- DNA repair and disease

Call for abstracts:

Abstract submission deadline: 29th of April, 2011