The Second ISSAT International Conference on Data Science in Business, Finance and Industry (DSBFI 2020) conference provides an international forum for presentation of new results as well as exchanges and disseminates innovative and practical development experiences. The conference covers all aspects of data science in business, finance and industry including algorithms, modeling and applications. Large amount of data created by various mobile platforms, social media interactions, e-commerce transactions, and IoT provide an opportunity for business, finance and industry to improve the quality of their products and services by effective use of data science. DSBFI draws researchers, application developers, and practitioners from a wide range of data science related areas such as statistics, business analytics, computer science, engineering, and applied science. By promoting novel, high-quality research findings and innovative solutions to challenging data science problems, the conference seeks to advance the state-of-the-art in data science.