| |||||||||||||
BMC Bioinf AIMM 2009 : BMC Bioinformatics Special Issue on Annotation, Interpretation and Management of Mutations | |||||||||||||
Link: http://www.ebi.ac.uk/Rebholz-srv/aimm.html | |||||||||||||
| |||||||||||||
Call For Papers | |||||||||||||
BMC Bioinformatics Special Issue: CALL FOR PAPERS
================================================= A special issue of the Journal will showcase original papers that address themes relevant to the: Annotation, Interpretation and Management of Mutations http://www.ebi.ac.uk/Rebholz-srv/aimm.html Mutations play a key role in the understanding of genetic mechanisms and complex diseases. A number of bioinformatics initiatives gather and store mutational relevant information (OMIM, GAD, HapMap, 1000 Genomces project, COSMIC, UniProtKb, PDB), but the challenge for data integration initiatives is to facilitate the interpretion of phenotypic / impact changes induced by the mutations. Solutions are required in the domains of: (i) text mining - for the identification of phenotypic / impact annotations, (ii) data warehousing and machine learning – to allow better integration of mutation relevant information into a bioinformatics infrastructure (e.g., ontologies, workflows, databases, machine learning techniques). Synergistic use of these technologies should facilitate inferences of knowledge from sequence to structure to function and to phenotypes. Authors may also focus on methods for the prediction of phenotypic effects induced by mutations, infrastructure to support clinical decision processes involving mutations as well as the management and aggregation of mutations with annotations from different digital or text resources. Suggested themes (but not limted to): - Mutation Databases and Metadata: Design, Content, Accuracy. - Extraction of mutations and annotations from literature - Methods and systems for predicting the impacts of Mutations - Mutation Data Integration, Phenotype Ontologies, Semantic Support and Reuse Published manuscripts will include a clear and motivating description of the specific challenge and biological context that they address and a lucid illustration of the proposed solution. Article-processing charges: ======================= Please note that the standard BMC Bioinformatics publication processing fees apply to submissions to this special issue. Please refer to http://www.biomedcentral.com/bmcbioinformatics/ifora/ for further information. Important Dates: =============== Submissions open: Dec 25th 2008 Submissions due*: February 14th 2009 Revised manuscript submitted: March 31st 2009 Submissions: ============ Pre-submission enquiries and variations to the deadlines above may be made in consultation with the Special Issue Editor bakerc@unb.ca * Author instructions can be obtained by sending an email to bmcmutations@gmail.com an automated reply will sent and complete submissions should also be sent to bmcmutations@gmail.com but with AIMM in the subject line. Special Issue Editors: ====================== Christopher J. O. Baker - University of New Brunswick, Canada Dietrich Rebholz-Schuhmann, European Bioinformatics Institute, UK |
|