posted by user: MAJ || 1540 views || tracked by 1 users: [display]

Metabolites 2018 : Cell Symposium: Metabolites as Signaling Molecules

FacebookTwitterLinkedInGoogle

Link: http://www.cell-symposia.com/metabolites-2018/
 
When Dec 9, 2018 - Dec 11, 2018
Where Seattle, WA, USA
Submission Deadline Jul 23, 2018
Categories    metabolites   molecular cell   epigenetics   metabolism
 

Call For Papers



Once thought of merely as byproducts of cellular metabolism, we now appreciate how metabolites can directly impact a myriad of processes, from signalling to gene expression, in cells. Cells adapt metabolism to allow ATP production and the redistribution of carbons to nucleotide, protein, and fatty acid syntheses to support their physiological functions. Metabolism can also influence cell state, with increasing evidence that changes in metabolite levels can affect both pathway regulation and gene expression, particularly through the effects of these metabolites on chromatin modifications. One example driven by genetic mutations is the role played by “oncometabolites,” which can impact the activity of enzymes that control epigenetic state. Such crosstalk between metabolism and epigenetics appears to be bi-directional, with multiple epigenetic enzymes acting as rheostats to readjust metabolism following nutrient changes. More recent studies determined that alterations in the microbiome influence availability of metabolites, in turn affecting signaling, cell proliferation, and chromatin. Lastly, changes in metabolites with age can impact both Sirtuins and PARP enzymes, influencing diverse pathways, including epigenetics and DNA repair.

This meeting will bring together scientists studying metabolites and their signaling properties and how they affect many aspects of health, including aging and cancer.

Topics:

Metabolite Regulation of Epigenetics
Metabolites and Signaling
Metabolites in Cancer
Metabolites in Organismal Physiology and Aging
Metabolites and the Microbiota

Related Resources

ME16   Metabolic Engineering 16
5th Cell Therapies and Immunotherapy Con 2024   5th Cell Therapies and Immunotherapy Conference
BLOCKISA 2025   BLOCKchain Infrastructure as a Service and its Applications
OASIS 4 2025   Ontology As Structured by the Interfaces with Semantics 4
AS 2024   20th International Conference on Applied Statistics
XR for the Metaverse 2024   IEEE MetroXRAINE 2024 - Special Session on Extended Reality as a gateway to the Metaverse
DAS 2024   Data Analytics as a Service – Challenges and Opportunities - Workshop
FGRT SCPC 2024   Frontiers in Genetics Research Topic - Single Cell RNA Expression in Pancreatic Cancer
Optogenetics 2024   4th Optogenetic Technologies and Applications Conference
Self-Organization in Biology 2024   Self-Organization in Biology Freiburg Spemann-Mangold Centennial Symposium