The series of BIBE Conferences, founded in 2000, is the longest-running IEEE Conference of its kind, inspiring many similar venues. The 20th annual IEEE International Conference on Bioinformatics and Bioengineering aims at building synergies among the complimentary disciplines of Bioinformatics, Bioengineering and Biomedical. These synergies have delivered advances for understanding a wide range of complex issues and problems in the fields of medicine, bioengineering and biological systems, health environmental science, public healthcare, food, forensics, wearable and assistive devices and more. These fields have improved the human condition by helping us understand living organisms at multiple levels, developing innovative implants and bio-prosthetics, and by improving tools and techniques for the detection, prevention and treatment of diseases. The BIBE series provide a common platform for the cross fertilization of ideas, and for shaping knowledge and scientific achievements by bridging these disciplines into an interactive and engaging forum.